Cannabinoids are compounds, primarily from cannabis, that interact with the body's endocannabinoid system, producing mental/physical effects, with notable types like psychoactive THC and non-psychoactive CBD; common effects include relaxation or anxiety, while side effects range from dry mouth and impaired memory to psychosis in heavy users, with THC also impacting driving.

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These compounds function by binding to cannabinoid receptors (CB1/CB2) to influence appetite, pain, mood, and memory, used medically for conditions like chronic pain, nausea, and epilepsy, though effects vary by cannabinoid and individual.